Fertility drugs are still the main treatment for women with ovulation disorders. Some of these drugs are eatable and some are injectable. These drugs work by releasing hormones that will initiate or regulate ovulation. The use of ovulation drugs alongside treatment methods increases the chances of pregnancy in women. Here you will find some of the common medications prescribed for infertility treatment.
One of the most common medications for infertility treatment is ovarian stimulating drugs for ovulation. Taking these medications can help your body release more mature eggs at one time. These medications are commonly used alongside assisted reproductive techniques such as IVF or IVF or IUI to increase the chance of pregnancy. Some of these types of drugs are as follows:
Clomiphene Citrate Pills: This drug, also known as Clomid or Serofen, is the first choice of physicians for infertility treatment and has been used for over 40 years. It releases hormones like follicle-stimulating hormone, gonadotropin-releasing gnrh, and luteinizing hormone or lh. These hormones stimulate the ovary to prepare eggs. The drug is usually given as a pill in a 5 mg daily dose for five days. It should usually start on the third to fifth day of the month, and you should expect ovulation after about seven days.
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This hormone is commonly used in combination with other fertility drugs to stimulate the ovary and release the ovum or mature eggs. This injectable is injected intramuscularly and one can learn it by doing it at home. Some brands of this drug, some foreign and some Iranian, include ivf-c, pregnyl, chorago and choriomon.
Follicle-Stimulating Hormone: This hormone stimulates egg production and growth in the ovary. The drug is usually given as a subcutaneous injection and should be injected subcutaneously and the individual can do this by training at home. Some of the names available in Iran include gonal-f, bravelle, urofollitropin, and karma. These medicines are available internally and externally and are prescribed by your doctor.
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Human menopausal gonadotropin hormone or hmg:
This drug is a combination of follicle stimulating hormone or lh and is currently one of the most powerful drugs for infertility treatment in Iran. This drug is available in Iranian market with names like menopur, menotropins, ivf-m and karma hmg.
Gonadotropin-releasing hormone or gnrh: This drug, unlike hmg drugs, which contains the luteinizing hormone and lh, stimulates the release of luteinizing hormone and lh from the pituitary gland. The drug is usually prescribed injectable and is available in Iran with the names relefact, lutrelef, lh-rh, and synafact and superfact.
Each of these drugs can be used to stimulate or control ovulation as a treatment for some of the infertility problems along with infertility and assisted fertility treatments. These medications are prescribed by a physician at different doses, either by injection or by pill, depending on the use. Some of the above-mentioned injectable drugs are injected under the skin and others into the muscle. The injection site may include the abdomen, arm, upper thigh or hip. Injections usually begin on the second or third day of the period cycle and continue for seven to four consecutive days. Your doctor will tell you the dosage and type of injection, which is also written in the medicine leaflet. Ovulation induction medications may cause mild side effects such as allergies, infections, swelling or bruising at the injection site. There is also the risk of ovarian hyperstimulation, a complication where the ovaries become large and painful. Ovulation-stimulating medications also increase the chance of multiple pregnancies, which can pose risks to mother and child.
Other medicines to help and improve fertility that may be prescribed by a doctor for women are listed below:
Aspirin: Research has shown that in certain cases, aspirin can reduce the risk of miscarriage. This medicine must be taken with a doctor’s diagnosis.
Heparin: A drug to reduce the risk of miscarriage in women who have experienced recurrent spontaneous abortion for specific reasons.
Modorell: This drug is a steroid that can help fertilize eggs for implantation. Moderol may be prescribed when the physician considers it necessary.
Antagon and Cetrotide: a family of ganirelixstate and an injectable drug used to inhibit premature ovulation in women undergoing fertility treatment.
Progesterone: Your doctor may prescribe progesterone as an intravenous injection or suppository a few days after the fetus is transferred to the uterus to prevent miscarriage. This hormone causes sufficient growth of the uterine wall for implantation
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Fertility drugs are generally safe and most who have it experience no problems with their health or pregnancy. However, there are some risks to be aware of, which include: bloating, headache, breast tenderness, upset stomach, hot flashes, and mood swings. The most common fertility drug risks are conceiving a multiple pregnancy (like twins or triplets or more) and developing ovarian hyperstimulation syndrome (OHSS).
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Clomiphene and gonadotropins are commonly used fertility drugs that can increase your chances of having twins, for every 20 pregnancies conceived with Clomid, only one will result in twins. Clomid, a pill taken by mouth to induce ovulation, causes twin pregnancies between 5% and 12% of the time.
Fertility drugs have a reputation for causing multiple pregnancies meaning more than one child is conceived at one time, resulting in twins, triplets, or even more babies.
If you’re taking Clomid (clomiphene), you may be nervous (or excited) about the prospect of having two or more babies at once. However, those newsworthy high-order multiple stories are more likely with injectable fertility drugs that are used during intrauterine insemination (IUI) or in-vitro fertilization (IVF) treatments.
You can expect to start ovulating about 7 days after you’ve taken the last dose. If it doesn’t happen right away, your doctor may ask you to increase your dose by 50 milligrams a day each month, up to 150 milligrams. After you start to ovulate, most doctors suggest taking clomiphene for no longer than 6 months. If you haven’t become pregnant after half a year, your doctor will probably prescribe a different medication or suggest that you see an infertility specialist.
How well it works: About 60% to 80% of women who take clomiphene will ovulate, and about half will be able to get pregnant. Most pregnancies happen within three cycles.
Clomid offers you an 80 percent chance of ovulating, usually within the first three months. Due to this ovulation boost, most women have a 50 percent chance of getting pregnant within the first six months after starting Clomid.
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The most common side effects include:
Some research suggests that certain fertility drugs increase the risk of ovarian and endometrial cancers, among others.
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Clomiphene citrate (Clomid, Serophene) is the most commonly-prescribed fertility drug for women. Doctors prescribe this drug for women who ovulate irregularly or not at all. Clomidcauses the pituitary gland to secrete more follicle stimulating hormone (FSH), which starts the development of ovarian follicles containing eggs. If this drug works, ovulation occurs and your ovary will release eggs.
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