The method of embryo transfer to the uterus or zift is similar to the IVF or gift method, except that in the zift method the doctor fertilizes the eggs before transferring the eggs to the uterus. Fertilized eggs are called egg cells or zygotes, which is the same single-cell embryo before dividing into several cells. The zift method is one of the methods of aggressive infertility treatment and its use is not common. Here's how you can get acquainted with zift infertility treatment.
If other treatments are unsuccessful and the woman has at least one open uterine tube, zift is a good way to increase the chance of fertility. The superiority of the zift method over the gift method is that the eggs are fertilized before being transferred to the uterus. In this way, the growing embryo reaches the uterus itself. If you have the following problems, your doctor may prescribe zift:
If male sperm count is too low or fertilization is difficult during the previous ivf period, zift can be performed with microinjection, which increases the chance of fertilization by direct injection of sperm into the egg.
The stages of ovulation induction and fertilization in the zift method are similar to that of the IVF method, but are then transplanted into the uterine tubes in the embryo zift method instead of the uterus. The steps to perform the zift procedure are as follows:
Ovarian Stimulation: Stimulation of the ovaries occurs with the use of certain medications in the first few days of the month, leading to the production of several mature eggs and preventing premature release of the eggs.
Follicular Growth: When taking these medications, you should see your doctor every two to three days for blood tests and ultrasound to have your hormone levels checked and follicles growth rate.
Puncture or ovulation: When the eggs are ready for extraction, the doctor at the hospital first examines the follicles using vaginal ultrasound and after identifying the appropriate follicles, inserting a narrow needle through the vaginal wall, about five to four eggs from the vagina. Into the follicles.
Fertilization: At this stage, a laboratory psychologist combines the eggs with the sperms and monitors fertilization closely. About one day later, each fertilized egg turns into a single-celled embryo called the zygote. Fertilization may be performed by microinjection. The next steps of the zift method are different from the ivf method, which follows:
Zygote Transfer: After the zygote develops, the doctor performs a laparoscopic operation. In this small operation, the doctor, after numbing the area, inserts a small incision in the abdomen, inserts a laparoscopic device into the abdomen, and transfers one to five pre-selected zygotes into the uterine cavity. After a laparoscopic procedure, you usually feel mild pain. Excess zygotes can be frozen and used in the future if treatment fails.
Embryo implantation: If successful above, a zygote grows and enters the uterus through the cervix and implants in the uterine wall. The embryo continues to grow after implantation and becomes an embryo. If more than one zygote is transmitted, the chance of pregnancy increases, but the probability of two or more pregnancies increases.
Pregnancy Test: Two weeks after laparoscopy, you can be sure you are pregnant using a pregnancy test.
Depending on the cause of infertility of each couple and their age, the results obtained by the zift method will be quite different. Younger women usually get better results because of healthier eggs. The statistics of the zift courses that give birth to at least one infant are similar to those of the ivf method. Because in the Zift method, fertilized or zygote eggs are transferred to the uterine tubes, they have an advantage over the gift method.
Although this treatment, like other fertility treatments, increases the chance of fertility, it also has its disadvantages. Here are some of the drawbacks and disadvantages of this method:
Expensive: The Zift method requires expensive laboratory, drug, and surgical procedures.
Time-consuming: It takes a long time to monitor how your body responds to medications, and you should see your doctor many times for blood tests and ultrasound.
Not Available: Many fertility clinics do not offer this method.
Need for Surgery: Unlike the ivf method, zigzag surgery requires invasive surgery in the uterine cavity.
Multiple Pregnancy: In this method, because more than one zygote is usually implanted in the uterus, two or more pregnancies are more likely, and although many couples consider this a blessing, being pregnant is a risk of miscarriage and other pregnancies. Increases complications.
Other Side Effects: Like IVF, the risk of preterm birth or a newborn weighing less than normal is also high. If your body responds too well to fertility drugs, you may have ovarian hyperstimulation syndrome (ohss). Although all assisted reproductive procedures have a risk of ectopic pregnancy, the risk is higher in the zift method.
Treatment may be incomplete: Treatment may be discontinued if symptoms of ovarian hyperstimulation syndrome or insufficient follicle production occur.