Most couples dream of starting a family but are often unable to due to infertility. They keep trying for years without any treatment, hoping to conceive but the result is rather disappointing. Infertility is a very common problem and can be treated with the advancement in technology but most often we consider this condition a taboo, making people hesitant to even talk about it.
IVF in Iran is a process that involves fertilisation of an egg with the sperm outside the body. The process involves stimulating the ovary to grow follicles (fluid-filled sacs in the ovary that contain eggs), monitoring this growth, when mature collecting these eggs via a small procedure, allowing sperm to fertilise the eggs in a laboratory, growing the fertilised egg in the lab and transferring it back to the womb after 3 to 5 days. It is called in vitro as the fertilisation occurs outside the body.
There are many causes of infertility among women. Some of them are listed below-
Advancing age in females
Drinking and smoking
Increased marital age
Fallopian tube injury
While a change in certain lifestyle habits can help you prevent this to a major extent. Certain causes need treatment. And that is a process called In Vitro Fertilization (IVF).
In vitro fertilization (IVF) is a treatment used to treat fertility or genetic problems and assist one with the conception of a child. During this process, mature eggs are retrieved from the ovaries and fertilized by sperm in a lab. Then the fertilized embryo or eggs are implanted in the uterus.
The IVF procedure involves five major steps mentioned below: IVF is the process of fertilization by manually combining an egg and sperm in a laboratory, and then transferring the embryo to the uterus.
Step 1: Stimulation of eggs through hormone therapy
The production of eggs is stimulated through a hormone therapy. Fertility drugs are given to the woman to boost the production of eggs. Normally, a woman produces one egg/month but the drugs enable the ovaries to produce several eggs which would help in the procedure further.
Step 2: Retrieving the eggs from the ovaries
The next step involves removing the eggs from the ovary. This is done through a minor surgery called ‘follicular aspiration’. This enables retrieving the eggs from the woman’s ovaries.
Step 3: Fertilization of the eggs and sperm
The male sperm is placed together with the best quality eggs. Eggs and sperm are then stored in an environmentally controlled chamber leading to fertilization. The sperm eventually enters (fertilizes) an egg within a few hours after insemination. However, if the doctor thinks the chances of fertilization is low, the sperm may be directly injected into the egg.
Step 4: Embryo culture
When the fertilized egg divides, it further develops into an embryo. The laboratory staff regularly check the embryo to make sure it matures properly. Within a matter of 3-5 days, a normal embryo matures, which has several cells that are actively dividing.
Step 5: Embryo transfer
Embryos are placed into the woman's uterus 3 - 5 days after egg retrieval and fertilization. Infertility as a problem has been prevalent in our country for quite some time but people aren’t or choose not to be aware of it. This is wrong on many levels. Every individual should be aware of this condition and the ones who are suffering should get themselves tested.
We at Parents of Fertility are battling the problem of rising infertility. We not only help you in testing your fertility levels but also help you understand the IVF process by connecting you to specialized IVF centres across India. The listed IVF Centres have the specialized consultants and the infrastructure needed to not only understand your condition but to also help you in the process of In Vitro Fertilization.
The success ratio rate for IVF depends on the age of the woman, cause of infertility, years of infertility, type of embryo transfer, quality of the sperm and whether self-eggs or donor eggs were used. The success rate is higher when frozen embryos are used as opposed to fresh embryos. Success is higher in younger women, so even when a woman has an embryo transfer, say in her 40s with embryos that were created when she was in her 30s, her chance of success is that of a woman in her 30s. Frozen cycles tend to have a higher success rate as the embryos that survive the thawing process will be more robust, resulting in higher chances of achieving a pregnancy. Donor eggs likewise come from a younger donor who is medically fit and hence tends to give better success rates. Better the sperm quality better the success rate.
Success in IVF is measured in various parameters for audit purposes. The fertilisation rate, implantation rate, clinical pregnancy rate, take home baby rate etc. Of significance is the live birth rate as this is the chance that any couple having treatment will take a baby home. Irrespective of the age of the patient, a live birth rate of around 30% is considered as gold standard around the world.
The procedure typically takes up to 17-20 days from the start of the period followed by 15 days of waiting to do a pregnancy test to find out if a pregnancy has occurred. Sometimes the procedure is done in 2 steps. Step 1 involves creating the embryos and freezing and then step 2 is preparing the womb at a later date for an embryo transfer.
It is highly recommended to avoid smoking and drinking alcohol when planning a pregnancy. Exposure to pesticides, any kind of chemicals and radiation should be avoided as much as you can. Medicines should not be taken without prior consultation from a medical expert. Always emphasise that you eat freshly cooked homemade food.
The first IVF cycle will often be successful at a high-quality IVF programme. One of the most frustrating situations for patients and clinicians is the failure of a well-progressing cycle. It is important to understand that IVF is not a miracle solution; instead, it is the most successful treatment when all other fertility treatments have failed.
The success rate of IVF/ICSI is in the range of 30-35% per embryo transfer. Hence, unfortunately, many couples may not conceive at their first cycle of IVF and will need to consider a second cycle. If it's been a perfect cycle with good quality of embryos and a good lining of the womb, then often all one needs to do is to repeat it until it works. This requires a lot of patience, fortitude and support from the treating team. When faced with such a situation do consider taking a break, understanding why your treatment didn’t work and planning your next step. Usually, a break of 2 to 3 months is recommended.
It is not necessary that while one opts for IVF, the couple will always have twins or triplets. World data suggests that when 2 good quality embryos are transferred on a day 3 after fertilisation the chance of twins is around 25%, interestingly when 2 good quality blastocysts of day 5 are transferred the twin rate is 50%. The success rate of IVF is not just measured on transferring of the number of embryos. However, the fertility experts successfully freeze the extra embryos and store them for future vitrification thus reducing the risk of multiple births.
When the sperm is of poor quality or the cover of the egg is thick and hard, ICSI comes to the rescue and helps fertilisation. ICSI is where sperm is directly injected inside an egg to achieve fertilisation. Women whose eggs have thicker covering shell (zona) also have trouble with implantation (sticking of the embryo to the lining of the womb) even after the embryo is formed. Thinning of this thick shell with a laser is called laser hatching. In cases of severe male factor infertility, PICSI or physiological ICSI allows us to select a physiologically normal sperm thus allowing a chance at a better-quality embryo.
Blastocyst culture is growing the egg in the lab until the 5th day after fertilisation. Such an embryo has a better chance of implantation. Similarly, a sequential transfer where double transfers are attempted in a single cycle e.g day 3 and day 5 one embryo each is another procedure used to increase the chance of success.
The IVF cost in Iran or anywhere else in the world is primarily dependent on your infertility workup. Hence it varies from person to person. If your friend, relative or colleague was lucky enough to have a baby by going through 2 IVF cycles, you may be fortunate by conceiving in one IVF cycle itself. Or perhaps a simple laparoscopy procedure might be enough to cure your infertility.
The IVF cost in Iran or around the globe is rising as more and more modern diagnostic test, and treatment methods (like IUI, hysteroscopy, laparoscopy) are being used to aid and facilitate infertility treatments cost. Because of this, there is no upper limit to the amount of money one can invest in their quest for a child. Thus it is crucial for all of us to know what the different kinds of ART treatments are.
Assisted Reproductive Technology also abbreviated as ART is the series of all fertility treatment options wherein both eggs, as well as, sperm are managed. ART processes include surgically extracting eggs from a woman’s ovaries, merging all of them with sperm in the laboratory, as well as restoring these to the woman’s body or perhaps donating these to yet another woman.
ivf cost in iran – In vitro fertilization is amongst the ART procedures of letting impregnation of the man as well as woman gametes (sperm as well as an egg) take place outside the woman’s body system. The IVF treatment cost in Iran is directly proportional to the type and number of times these techniques are used which are as enumerated below.
IVF Cost For Specific procedures utilized in in-vitro fertilization are:
Transvaginal ovum retrieval (OVR) is the procedure wherein a tiny needle is placed through the rear of the vagina as well as led by ultrasound into the ovarian follicles to gather the fluids which contain the eggs. Embryo transfer is the part of the procedure wherein just one or perhaps many embryos are put into the uterus of the woman with the intention to set up a conception.
IUI or artificial insemination is a type of aided pregnancy wherein a catheter is employed to put sperm straight into the uterus next to your egg during ovulation. The sperm initially undergoes a laboratory process to eliminate lethargic sperm and then keep only fast-moving sperm to enhance the quantity of sperm that arrives at the egg, which improves the possibilities of having a child. This process is usually coupled with more than one fertility medications.
Artificial insemination is suggested in conditions of moderate endometriosis or even unexplained female infertility but is not for infertility on account of a male element. It is an efficient, secure, as well as an inexpensive way for dealing with infertility which is suitable for young partners since the success levels for IUI decline considerably in ladies over thirty-five.
Besides knowing artificial insemination expenses, it’s also wise to learn how many cycles you may need so that you can get pregnant; since this can help you get a much better idea of your current IUI Cost expenses.