PICSI IVF

PICSI IVF

Indications for PICSI/ICSI

Good candidate for PICSI

Is PICSI better than ICSI?

What is PICSI in IVF?

Which is better IUI or IVF?

How is ICSI different from IVF?

PICSI

To determine the efficacy of the physiological ICSI technique (PICSI) vs. conventional ICSI in the prognosis of couples with male factor, with respect to the following outcome measures: live births, clinical pregnancy, implantation, embryo quality, fertilization and miscarriage rates. Intracytoplasmic sperm injection (ICSI) is a laboratory procedure developed to help infertile couples undergoing in‐ vitro fertilization (IVF) due to severe male factor infertility.  ICSI involves the insertion of a single sperm directly into the cytoplasm of a mature egg (oocyte) using a microinjection pipette (glass needle).  ICSI has been available for more than fifteen years and achieves a high overall fertilization rate.

There is now an alternative to the standard ICSI procedure called the PICSI procedure.  This alternative to the standard ICSI was developed to help in the selection of sperm by the laboratory staff.  The PICSI procedure does this by using a tissue media that is commonly used in the in‐vitro fertilization lab today and it is also a major component that surrounds the cells of the egg. 

Read more about : Type of Infertility Treatment in Iran

Read more about : Egg donation in iran

Read more about: iui vs ivf vs icsi

Indications for PICSI/ICSI

  • Very low numbers of motile sperm with normal appearance.
  • Problems with sperm binding to and penetrating the egg.
  • Prior or repeated fertilization failure with standard IVF culture and fertilization methods.
  • Frozen sperm collected prior to cancer treatment that may be limited in number and quality.
  • Absence of sperm secondary to blockage or abnormality of the ejaculatory ducts that allow sperm to move from the testes.  In this situation, sperm are obtained from the epididymis by a procedure called microsurgical epididymal sperm aspiration (MESA).
  • Absence of sperm in the ejaculate, but presence of sperm in the testes.  Sperm can be obtained by testicular biopsy.

Read more about: ICSI babies health problems

 

 

Good candidate for PICSI

PICSI is highly recommended in these particular cases:

  • Previous failure or low fertilisation even after ICSI.
  • Low embryo quality or their failure to develop (not related to poor egg quality).
  • Repeated miscarriages.

Read more about: ICSI IVF risks

Is PICSI better than ICSI?

The procedure is very simple for the lab and the major difference between what the ordinary ICSI procedure and the PICSI procedure is the actual dish with the hyaluronan. Physiological intracytoplasmic sperm injection (PICSI) did not significantly improve live birth rates compared with standard intracytoplasmic sperm injection (ICSI), and there was no difference between groups in either clinical pregnancy or premature birth, according to findings from a hyaluronic acid-binding sperm.

Read more about: ICSI IVF procedure in Iran

What is PICSI in IVF?

PICSI is a technique used to select sperm to use in ICSI treatment. It involves placing sperm with hyaluronic acid (HA), a natural compound in the body. PICSI identifies sperm that can bind to HA and these sperm are selected for use in treatment.

Read more about: ICSI success rate after embryo transfer

Which is better IUI or IVF?

IUI is often the first treatment suggested to those who want to conceive as it's less invasive and demanding than IVF. It's also much more affordable. If you are a woman under 35, most doctors will suggest 3 to 6 cycles of IUI before moving to IVF. With IUI, women under 35 often have a 10 to 15 percent chance of getting pregnant with just one cycle. With an IVF cycle using a woman's own eggs, the average national success rates range from 45 percent to 50 percent or more for patients under 35 years old.

Read more about: How long does it take to get pregnant with ICSI

How is ICSI different from IVF?

Research shows that IVF is just as effective as the ICSI procedure, where sperm is injected directly into an egg, when there is no male infertility factor. The key difference between IVF and ICSI is how the sperm fertilises the egg. In IVF, the egg and sperm (of which there are multiple) are left in a petri dish to fertilise on their own. In ICSI, one sperm is directly injected into the egg.

Read more about: ICSI IVF twins

10 common questions about PICSI IVF

1What is Picsi in IVF?
PICSI. ... PICSI is a method of selecting the best possible sperm for fertilisation before injection into the egg in the IVF protocol. Sperm are placed in the PICSI dish containing samples of hyaluronan (a naturally occurring biopolymer found in all human cells) hydrogel.
2Is Picsi better than ICSI?
Sperm that binds to the hyaluronan show improved DNA integrity and fewer DNA mistakes than those that do not bind. PICSI/ICSI is not a perfect technique. It is rare but eggs may be damaged by the PICSI/ICSI process
3What is the difference between ICSI and IVF?
The key difference between IVF and ICSI is how the sperm fertilises the egg. In IVF, the egg and sperm (of which there are multiple) are left in a petri dish to fertilise on their own. In ICSI, one sperm is directly injected into the egg
4Is ICSI better than IVF?
Is ICSI better than IVF? It depends. Research shows that IVF is just as effective as the ICSI procedure, where sperm is injected directly into an egg, when there is no male infertility factor. Cumulative live birth rates in Victoria were similar for IVF and ICSI in these circumstances.
5What is assisted hatching in IVF?
Assisted hatching is a fertility technique, used as part of IVF treatments, to facilitate the embryo hatching and implantation process. A fertilized embryo is covered by a shell, called the zona pellucida. ... Once the zona is sufficiently thinned, it tears allowing the embryo to hatch
6What is IMSI in IVF?
Intracytoplasmic morphologically selected sperm injection (IMSI) is a technique used in IVF treatment to examine and select sperm using a high-magnification digital imaging microscope for microinjection into the egg
7How long does fertilization take after ICSI?
Approximately six hours after egg retrieval, fertilization is accomplished by placing a small concentration of sperm onto each egg, or by intracytoplasmic sperm injection (ICSI). This is where a single sperm is injected into an egg.
8What is the difference between ICSI and IMSI?
Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction. Background: sperm micromanipulation, such as intracytoplasmic sperm injection (ICSI), is very useful for treating couples in which the male partner has a reduced sperm concentration or motility, or both
9Is ICSI more expensive than IVF?
ICSI is a more expensive procedure than IVF . ICSI has been in use for a shorter time than IVF. So experts are still learning about its possible effects.
10Does IVF guarantee healthy baby?
About 5 million kids worldwide have been born from IVF, says Hershlag, and most are healthy. ... Based on the available data, “in general we tell parents that IVF is safe and to a large degree, babies born from IVF are healthy and grow into healthy adults,” says Hershlag.

[kkstarratings]

6 Comments

  1. nadia says:

    How long should I stay in Iran to get pregnant with IVF?

    • Iranian Surgery Adviser says:

      Generally, one cycle of IVF takes about two months. Women younger than age 35 will get pregnant and have a baby with their first IVF egg retrieval and subsequent embryo transfer(s) about half the time. So age is an important factor but not the only one. You may need to have egg/sperm donation or even surrogacy, and time of your stay for each process is different. However for most of our cases we recommend 1 month or even less. To receive specific answer based on your medical documents, please contact our consultant via Whatsapp number +98 922 176 2312 . It’s a free service.

  2. jordan says:

    I’m looking for ivf and meanwhile my husband doesn’t have a viable sperm and we were wondering if Picsi would be a good method and if you can give a short explanation of how Picsi works?
    regards Elizabeth

    • Iranian Surgery Adviser says:

      As for choosing a method you should have a consult with our agents via what’s app on this number +98922 176 2312
      and as for Picsi explanation and how it’s done :
      It involves placing sperm with hyaluronic acid (HA), a natural compound found in the body. PICSI identifies sperm that can bind to HA and these sperm are selected for use in treatment. PICSI is a non-invasive procedure performed on a semen sample as an additional step in the ICSI process.

  3. yuen says:

    Hello, I want to know if in ICSI, when they want to put the fertilized sperm and egg in a woman’s uterus, is a cesarean section performed? A part of the woman’s body is cut or there is another method?

    • Iranian Surgery Adviser says:

      Dear Yuen, there would be no incisions for transferring embryos. The embryo is loaded into a catheter(a flexible tube), which is passed through the vagina and cervix and into the uterus where it is deposited.

Leave a Reply

Your email address will not be published. Required fields are marked *

Patient Review