What is stage 3 rectal cancer?

What is stage 3 rectal cancer?

What is stage 3 rectal cancer?

What is the survival rate of stage 3 rectal cancer?

Can Stage 3 rectal cancer be cured?

Does rectal cancer spread fast?

How long can you live with rectal cancer?

 

Stage III rectal cancer is divided into stages IIIA, IIIB, and IIIC.

Stage IIIA rectal cancer. Cancer has spread through the mucosa of the rectum wall to the submucosa and may have spread to the muscle layer, and has spread to one to three nearby lymph nodes or tissues near the lymph nodes. OR, cancer has spread through the mucosa to the submucosa and four to six nearby lymph nodes.

Most people with stage III rectal cancer will be treated with chemotherapy, radiation therapy, and surgery, although the order of these treatments might differ.

 

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Most often, chemo is given along with radiation therapy (called chemoradiation) first. This may shrink the cancer, often making it easier to take out larger tumors. It also lowers the chance that the cancer will come back in the pelvis. Giving radiation before surgery also tends to lead to fewer problems than giving it after surgery.

Chemoradiation is followed by surgery to remove the rectal tumor and nearby lymph nodes, usually by low anterior resection (LAR), proctectomy with colo-anal anastomosis, or abdominoperineal resection (APR), depending on where the cancer is in the rectum. If the cancer has reached nearby organs, a more extensive operation known as pelvic exenteration may be needed.

After surgery, chemo is given, usually for about 6 months. The most common regimens include FOLFOX (oxaliplatin, 5-FU, and leucovorin), 5-FU and leucovorin, CAPEOX (capecitabine plus oxaliplatin), or capecitabine alone. Your doctor will recommend the one best suited to your health needs.

Another option might be to get chemotherapy alone first, followed by chemo plus radiation therapy, then followed by surgery.

For people who can’t have chemo plus radiation for some reason, surgery (such as an LAR, proctectomy with colo-anal anastomosis, or APR) might be the first treatment. This might be followed by chemotherapy, sometimes along with radiation therapy.

 

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What is stage 3 rectal cancer?

Stage III rectal cancers have spread to nearby lymph nodes but not to other parts of the body.

Most people with stage III rectal cancer will be treated with chemotherapy, radiation therapy, and surgery, although the order of these treatments might differ.

What is the survival rate of stage 3 rectal cancer?

For rectal cancer, the overall 5-year survival rate for people is 67%. If the cancer is diagnosed at a localized stage, the survival rate is 89%. If the cancer has spread to surrounding tissues or organs and/or the regional lymph nodes, the 5-year survival rate is 71%. If the cancer has spread to distant parts of the body, the 5-year survival rate is 15%. Stage I cancers have a survival rate of 80-95 percent. Stage II tumors have survival rates ranging from 55 to 80 percent. A stage III colon cancer has about a 40 percent chance of cure and a patient with a stage IV tumor has only a 10 percent chance of a cure.

 

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Can Stage 3 rectal cancer be cured?

In general, stages 0, I, II, and III are often curable with surgery. However, many people with stage III colorectal cancer, and some with stage II, receive chemotherapy after surgery to increase the chance of eliminating the disease. People with stage II and III rectal cancer will also receive radiation therapy with chemotherapy either before or after surgery. Stage IV is not often curable, but it is treatable, and the growth of the cancer and the symptoms of the disease can be managed. Clinical trials are also a treatment option for each stage. Treatment usually involves surgical removal of the tumor followed by adjuvant chemotherapy. A clinical trial may also an option. For rectal cancer, radiation therapy may be used with chemotherapy before or after surgery, along with adjuvant chemotherapy.

 

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Does rectal cancer spread fast?

Rectal cancer most often spreads to the liver. This happens in part because the blood supply from the large intestine, which includes the rectum, is connected to the liver through a large blood vessel. colorectal cancers can be graded low grade or high grade. Grade focuses on how different the cancer cells look from a normal cell. High grade cancers have a tendency to grow and spread more rapidly. In most cases, colon and rectal cancers grow slowly over many years.

 

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How long can you live with rectal cancer?

Survival rates for any cancer are often reported by stage, the extent of spread when the cancer is identified. For colon and rectum cancer, around 39% are diagnosed at the local stage, before the cancer has spread outside the local area. The five-year survival for these patients with localized colon and rectum cancer is around 90%.

When the cancer has spread to the regional lymph nodes near the site of origin, the five-year survival rate is about 71%. When the cancer has metastasized to distant sites in the body (stage IV cancer), the five-year survival rate lowers to about 14%.

 

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10 common questions about Rectal Cancer Stage 3

1Can Stage 3 rectal cancer be cured?
Stage III rectal cancers have spread to nearby lymph nodes but not to other parts of the body. Most people with stage III rectal cancer will be treated with chemotherapy, radiation therapy, and surgery, although the order of these treatments might differ. ... After surgery, chemo is given, usually for about 6 months.
2What are the chances of surviving stage 3 rectal cancer?
Stage I cancers have a survival rate of 80-95 percent. Stage II tumors have survival rates ranging from 55 to 80 percent. A stage III colon cancer has about a 40 percent chance of cure and a patient with a stage IV tumor has only a 10 percent chance of a cure.
3How long do you live with rectal cancer?
Currently, there are around 1 million colorectal cancer survivors in the United States. Overall, the 5-year survival rate tells you what percent of people live at least 5 years after the cancer is found. Percent means how many out of 100. The 5-year survival rate for people with colorectal cancer is 65%.
4How do you get rectal cancer?
Rectal cancer develops usually over years; its actual cause is not known, but risk factors include increasing age (over 50), smoking, family history, high-fat diet, or a history of polyps or colorectal cancer or inflammatory bowel disease.
5Is rectal cancer worse than colon cancer?
Among them, colon cancer patients had better survival than those with rectal cancer, by a margin of 4 months in stage IIB. ... The prognosis of rectal cancer was not worse than that of colon cancer. Local advanced colorectal cancer had a poorer prognosis than local regional lymph node metastasis
6Is rectal cancer painful?
The most common symptoms of rectal cancer are a change in bowel habits, such as constipation or diarrhea, narrow shaped stools, or blood in your stool. You may also have pelvic or lower abdominal pain, unexplained weight loss, or feel tired all the time.
7Is rectal cancer fatal?
Recurrent Cancer In the early stages, colon cancer is one of the most curable cancers. In the later stages, it is the second most deadly. Colon cancer is the second leading cause of death from cancer in America (lung cancer is the first)
8Is rectal cancer dangerous?
Hyperplastic polyps are tiny and have no potential to turn cancerous. But adenomatous polyps can be dangerous, depending largely on size. Growths less than 5 millimeters across almost never cause trouble, but growths more than 2 centimeters across have a 50-50 chance of becoming cancerous within 10 to 15 years
9Is Stage 3 cancer curable?
Because stage 3 breast cancer has spread outside the breast, it's harder to treat than early stage breast cancer. With aggressive treatment, stage 3 breast cancer is curable, but the risk that the cancer will grow back after treatment is high.
10Where does rectal cancer usually spread to?
The most common site of metastases for colon or rectal cancer is the liver. Colorectal cancer cells may also spread to the lungs, bones, brain or spinal cord. If you have been treated for colorectal cancer and cancer cells have been found in these areas, it may be a sign that the original colorectal cancer has spread.

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