Bone cancer causes

Bone cancer causes and symptoms

How can you prevent bone cancer?

Is bone cancer curable?

How long do you live after being diagnosed with bone cancer?

Bone cancer causes

The exact reason why this happens is often not known, but certain things can increase your chance of developing the condition.

The following factors may raise a person’s risk of developing bone cancer:

Children with familial retinoblastoma, which is a type of eye cancer, have an increased risk of developing osteosarcoma. People with a history of sarcomas in their family, as is seen with Li-Fraumeni syndrome, are also at high risk for osteosarcomas. Researchers are finding genes that are passed from generation to generation that give people a higher risk of developing osteosarcoma than the general population. All of these conditions are rare.
Previous radiation therapy. People who have had radiation treatment for other conditions have a higher risk of developing bone cancer at the site of the radiation therapy. The majority of radiation therapy-caused sarcomas include angiosarcoma and undifferentiated pleomorphic sarcoma (UPS) of soft tissue or osteosarcoma, but other types may occur.
Chemotherapy for another cancer.Some drugs used to treat cancer, including alkylating agents and anthracyclines, may increase the risk of developing a secondary cancer, usually osteosarcoma.
Benign tumors or other bone conditions.Paget’s disease of the bone may lead to osteosarcoma. Other noncancerous bone diseases, such as fibrous dysplasia, may increase the risk of osteosarcoma.

Most bone cancers are not caused by inherited DNA mutations. They're the result of mutations during the person’s lifetime. These mutations may result from exposure to radiation or cancer-causing chemicals, but most often they occur for no apparent reason. These mutations are present only in the cancer cells, so they cannot be passed on to the person’s children.

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Bone cancer symptoms

Bone cancer can affect any bone, but most cases develop in the long bones of the legs or upper arms.

The main symptoms include:

persistent bone pain that gets worse over time and continues into the night
swelling and redness (inflammation) over a bone, which can make movement difficult if the affected bone is near a joint
a noticeable lump over a bone
a weak bone that breaks (fractures) more easily than normal

How can you prevent bone cancer?

Different factors cause different types of cancer. Researchers continue to look into what factors cause bone sarcoma, including ways to prevent it. Currently, there is no known way to prevent bone sarcoma.
Early detection offers the best chance for successful treatment, so people with known risk factors are encouraged to visit the doctor regularly and discuss their personal risk for developing bone sarcoma. This includes people with Li-Fraumeni syndrome, retinoblastoma, or other conditions in which the

risk of sarcoma is inherited. Talk with your health care team for more information about your personal risk of cancer. Still, most bone sarcomas occur in people with no known risk factors.

Is bone cancer curable?

For some people with bone cancer, treatment may remove or destroy the cancer. Completing treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it's hard not to worry about cancer coming back. This is very common if you've had cancer.

For other people, the cancer might never go away completely. Some people may get regular treatment with chemotherapy or targeted therapy or other treatments to try and help keep the cancer in check. Learning to live with cancer that does not go away can be difficult and very stressful.

The prognosis, or outlook, for survival for bone cancer patients depends upon the particular type of cancer and the extent to which it has spread. The overall five-year survival rate for all bone cancers in adults and children is about 70%. Chondrosarcomas in adults have an overall five-year survival rate of about 80%.

How long do you live after being diagnosed with bone cancer?

almost 85 out of every 100 people (almost 85%) survive their cancer for 1 year or more after diagnosis
more than 60 out of every 100 people (more than 60%) survive their cancer for 5 years or more after diagnosis
55 out of every 100 people (55%) survive their cancer for 10 years or more after diagnosis

10 common questions about bone cancer causes

1Is bone cancer curable?

2How long do you live after being diagnosed with bone cancer?

For example, if the 5-year relative survival rate for a specific type and stage of bone cancer is 80%, it means that people who have that cancer are, on average, about 80% as likely as people who don't have that cancer to live for at least 5 years after being diagnosed

3What are the causes of bone marrow cancer?

The most common type of bone marrow cancer is multiple myeloma. It starts in the plasma cells. These are white blood cells that make antibodies to protect your body from foreign invaders. Tumors form when your body starts to produce too many plasma cells

4What is the first sign of bone cancer?

Possible symptoms of bone cancer include: Bone pain: Pain is the most common sign of bone cancer, and may become more noticeable as the tumor grows. Bone pain can cause a dull or deep ache in a bone or bone region (e.g., back, pelvis, legs, ribs, arms).

5Where does bone marrow cancer start?

What Is Bone Marrow Cancer? Bone marrow cancer is a form of cancer that starts in the spongy tissue -- the marrow -- inside your bones. Marrow's main job is to make blood cells. There are many different types of blood and bone marrow cancer

6Can Bone Cancer kill you?

Cancer in the bones can affect the calcium balance of the body. ... If calcium continues to go up, it will cause you to become unconscious and eventually die. Cancer cells can affect the bone marrow. Eventually you might not have enough healthy bone marrow to make blood cells.

7Can you feel bone cancer?

The earliest symptoms of bone cancer are pain and swelling where the tumor is located. The pain may come and go at first. Then it can become more severe and steady later. The pain may get worse with movement, and there may be swelling in nearby soft tissue.

8Can chemo cure bone cancer?

Total remission: Chemotherapy aims to cure the patient. In some cases, chemotherapy alone can get rid of the cancer completely. Combination therapy: Chemotherapy can help other therapies, such as radiotherapy or surgery, produce better results.

9Is bone cancer aggressive?

This is often a very aggressive cancer, and it can spread (metastasize) to the lungs. Ewing's sarcoma is a very aggressive bone cancer. ... It can also spread to the lungs and lymphatic system. Malignant fibrous histiocytoma (MFH) is a rare type of cancer which more commonly arises from soft tissues than from bone

10Is Stage 4 cancer curable?

In later stages, the tumor may be any size. Stage 4 pancreatic cancer has spread to other organs. This means that surgeons cannot remove it, and there is no cure. Treatment involves managing pain and other symptoms to improve a person's quality of life

Bone cancer causes