BPH treatment drugs

BPH treatment drugs

BPH treatment drugs

Medication

Medication is the most common treatment for mild to moderate symptoms of prostate enlargement. The options include:

  • Alpha blockers.These medications relax bladder neck muscles and muscle fibers in the prostate, making urination easier. Alpha blockers — which include alfuzosin (Uroxatral), doxazosin (Cardura), tamsulosin (Flomax) and silodosin (Rapaflo) — usually work quickly in men with relatively small prostates. Side effects might include dizziness and a harmless condition in which semen goes back into the bladder instead of out the tip of the penis (retrograde ejaculation).
  • 5-alpha reductase inhibitors.These medications shrink your prostate by preventing hormonal changes that cause prostate growth. These medications — which include finasteride (Proscar) and dutasteride (Avodart) — might take up to six months to be effective. Side effects include retrograde ejaculation.
  • Combination drug therapy.Your doctor might recommend taking an alpha blocker and a 5-alpha reductase inhibitor at the same time if either medication alone isn't effective.
  • Tadalafil (Cialis).Studies suggest this medication, which is often used to treat erectile dysfunction, can also treat prostate enlargement.

Alpha-blockers

Alpha-blockers can help treat BPH. These drugs also work by helping to relax certain muscles, including your bladder outlet muscles. This makes it easier for people with BPH to pass urine. With better urine flow, you’ll be able to empty your bladder more completely.

Most people take alpha-blockers for BPH long-term, often for life. These drugs can give you relief quickly. They work within a few days or couple of weeks of when you start taking them.

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Alpha-blockers for BPH include:

  • alfuzosin (Uroxatral)
  • prazosin (Minipress)
  • terazosin (Hytrin)
  • doxazosin (Cardura)
  • silodosin (Rapaflo)
  • tamsulosin (Flomax)

Alpha-blockers are often also used to lower blood pressure. They help keep your arteries open to improve blood flow. Because these drugs lower blood pressure, they may cause lightheadedness or dizziness in people who take them for BPH. For this reason, you should stand up slowly from sitting or lying positions, especially during your first few days of treatment.

5-alpha reductase inhibitors

These drugs are often prescribed to men with especially large prostates. They interfere with the hormones that promote prostate growth. This helps slow the growth of the prostate and in turn eases BPH symptoms.

You’ll take these drugs for life to ease your BPH symptoms. These medications can take several months to work fully. Examples of 5-alpha reductase inhibitors include:

  • finasteride (Proscar, Propecia)
  • dutasteride (Avodart)
  • dutasteride/tamsulosin (Jalyn)

Combination therapy and another option

Some men see the best results by taking both an alpha-blocker and a 5-alpha reductase inhibitor. Taking both medications may work better to ease your symptoms, but you may also have a higher risk of side effects from one or both drugs.

You shouldn’t take tadalafil or any other PDE-5 inhibitor in combination with alpha-blockers.

Tadalafil (Cialis)

Cialis is the brand name for tadalafil, a drug used to treat erectile dysfunction. It is similar to Viagra and Levitra. Under the brand name Adcirca, tadalafil is used for pulmonary arterial hypertension.

Cialis increases blood flow to the penis, and this enables a man to achieve an erection. It does not lead to sexual arousal. It should be used with caution, and only under medical supervision.

Tadalafil was approved by the United States (U.S.) Food and Drug Administration (FDA) in 2003 for the treatment of erectile dysfunction (ED). It is also used to treat pulmonary arterial hypertension and benign prostatic hyperplasia, a condition in which the prostate gland becomes enlarged, causing problems with urination.

 

10 common question about BPH treatment drugs

1What is the latest treatment for BPH?
Several surgery options are also available, including transurethral resection of the prostate (TURP), which is considered the gold standard for treatment of BPH. However, TURP requires full anesthesia, an overnight hospital stay, three to six weeks of recovery time and is associated with sexual side effects.
2Can enlarged prostate be cured with medicine?
A range of treatments can relieve enlarged prostate symptoms -- medications, minimally-invasive office procedures, and surgery. The best one for you depends on your symptoms, how severe they are, and whether you have other medical conditions.
3What medications should be avoided with BPH?
Men with BPH should avoid any medications for colds and allergies that contain decongestants, such as pseudoephedrine (Sudafed, generic). Such drugs, known as adrenergics, can worsen urinary symptoms by preventing muscles in the prostate and bladder neck from relaxing to allow urine to flow freely.
4Which alpha blocker is best for BPH?
Alpha blockers are the most effective, least costly, and best tolerated of the drugs for relieving LUTS. Four long-acting alpha 1 blockers are approved by the Food and Drug Administration for treatment of symptomatic LUTS/BPH: terazosin, doxazosin, tamsulosin, and alfuzosin.
5Which drug is best for BPH?
If you have high blood pressure and BPH, alpha blockers may be a good option for you because they treat both conditions. ... Names: Your doctor might suggest one of these alpha blockers: Alfuzosin (Uroxatral) Doxazosin (Cardura) Prazosin (Minipress) Silodosin (Rapaflo) Tamsulosin (Flomax) Terazosin (Hytrin)
6Can BPH be cured permanently?
Although there is no cure for benign prostatic hyperplasia (BPH), also known as enlarged prostate, there are many useful options for treating the problem. Treatments focus on prostate growth, which is the cause of BPH symptoms. Once prostate growth starts, it often continues unless medical therapy is started.
7Does drinking water help enlarged prostate?
If you have BPH or prostatitis, make an effort to reduce your caffeine intake by cutting back on coffee, soda or energy drinks. ... Another important drink for you prostate is water. Stay hydrated, and do not try to drink less to reduce your urine.
8Is lemon good for enlarged prostate?
This is thought to target cancer cells and promote a healthy prostate. ... Citrus: Oranges, lemons, limes, and grapefruits are all high in vitamin C, which may help to protect the prostate gland. Onions and garlic: One study found that men with BPH tended to eat less garlic and onions that men without BPH.
9Is lemon good for enlarged prostate?
This is thought to target cancer cells and promote a healthy prostate. ... Citrus: Oranges, lemons, limes, and grapefruits are all high in vitamin C, which may help to protect the prostate gland. Onions and garlic: One study found that men with BPH tended to eat less garlic and onions that men without BPH.Feb 28, 2018
10What will shrink an enlarged prostate?
There are several treatment options for an enlarged prostate. You can take alpha-blockers such as terazosin (Hytrin) or tamsulosin (Flomax) to help relax the prostate and bladder muscles. You can also take dutasteride (Avodart) or finasteride (Proscar), a different kind of medication for reducing BPH symptoms.

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