Conjoined Twins

What are Conjoined Twins?

Conjoined twins are two babies who are born physically connected to each other.

Conjoined twins develop when an early embryo only partially separates to form two individuals. Although two fetuses will develop from this embryo, they will remain physically connected — most often at the chest, abdomen or pelvis. Conjoined twins may also share one or more internal organs.

Though many conjoined twins are not alive when born (stillborn) or die shortly after birth, advances in surgery and technology have improved survival rates. Some surviving conjoined twins can be surgically separated. The success of surgery depends on where the twins are joined and how many and which organs are shared, as well as the experience and skill of the surgical team.

About Iranian Surgery

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Before Conjoined Twins Treatment

Symptoms

There are no specific signs or symptoms that indicate a conjoined twin pregnancy. As with other twin pregnancies, the uterus may grow faster than with a single fetus, and there may be more fatigue, nausea and vomiting early in the pregnancy. Conjoined twins can be diagnosed early in the pregnancy using standard ultrasound.

How twins are joined

Conjoined twins are typically classified according to where they’re joined, usually at matching sites, and sometimes at more than one site. They sometimes share organs or other parts of their bodies. The specific anatomy of each pair of conjoined twins is unique.

Conjoined twins may be joined at any of these sites:

. Chest. Thoracopagus twins are joined face to face at the chest. They often have a shared heart and may also share one liver and upper intestine. This is one of the most common sites of conjoined twins.

. Abdomen. Omphalopagus twins are joined near the bellybutton. Many omphalopagus twins share the liver, and some share the lower part of the small intestine (ileum) and colon. They generally do not share a heart.

. Base of spine. Pygopagus twins are commonly joined back to back at the base of the spine and the buttocks. Some pygopagus twins share the lower gastrointestinal tract, and a few share the genital and urinary organs.

. Length of spine. Rachipagus, also called rachiopagus, twins are joined back to back along the length of the spine. This type is very rare.

. Pelvis. Ischiopagus twins are joined at the pelvis, either face to face or end to end. Many ischiopagus twins share the lower gastrointestinal tract, as well as the liver and genital and urinary tract organs. Each twin may have two legs or, less commonly, the twins share two or three legs.

. Trunk. Parapagus twins are joined side to side at the pelvis and part or all of the abdomen and chest, but with separate heads. The twins can have two, three or four arms and two or three legs.

. Head. Craniopagus twins are joined at the back, top or side of the head, but not the face. Craniopagus twins share a portion of the skull. But their brains are usually separate, though they may share some brain tissue.

. Head and chest. Cephalopagus twins are joined at the face and upper body. The faces are on opposite sides of a single shared head, and they share a brain. These twins rarely survive.

In rare cases, twins may be conjoined with one twin smaller and less fully formed than the other (asymmetric conjoined twins). In extremely rare cases, one twin may be found partially developed within the other twin (fetus in fetu).

Causes

Identical twins (monozygotic twins) occur when a single fertilized egg splits and develops into two individuals. Eight to 12 days after conception, the embryonic layers that will split to form monozygotic twins begin to develop into specific organs and structures.

It’s believed that when the embryo splits later than this — usually between 13 and 15 days after conception — separation stops before the process is complete, and the resulting twins are conjoined.

An alternative theory suggests that two separate embryos may somehow fuse together in early development.

What might cause either scenario to occur is unknown.

Risk factors

Because conjoined twins are so rare, and the cause isn’t clear, it’s unknown what might make some couples more likely to have conjoined twins.

Complications

Pregnancy with conjoined twins is complex and greatly increases the risk of serious complications. Conjoined babies require surgical delivery by cesarean section (C-section) due to their anatomy.

As with twins, conjoined babies are likely to be born prematurely, and one or both could be stillborn or die shortly after birth. Severe health issues for twins can occur immediately — such as trouble breathing or heart problems — and later in life, such as scoliosis, cerebral palsy or learning disabilities.

Potential complications depend on where the twins are joined, which organs or other parts of the body they share, and the expertise and experience of the health care team. When conjoined twins are expected, the family and the health care team need to discuss in detail the possible complications and how to prepare for them.

Diagnosis

Conjoined twins can be diagnosed using standard ultrasound as early as the end of the first trimester. More-detailed ultrasounds and echocardiograms can be used about halfway through pregnancy to better determine the extent of the twins’ connection and the functioning of their organs.

If an ultrasound detects conjoined twins, a magnetic resonance imaging (MRI) scan may be done. The MRI may provide greater detail about where the conjoined twins are connected and which organs they share. Fetal MRI and fetal echocardiography assist with planning for care during and after pregnancy.

During Conjoined Twins Treatment

Treatment

Treatment of conjoined twins depends on their unique circumstances — their health issues, where they’re joined, whether they share organs or other vital structures, and other possible complications.

Monitoring during pregnancy

If you’re carrying conjoined twins, you should be closely monitored throughout your pregnancy. You’ll likely be referred to a maternal and fetal medicine doctor who specializes in high-risk pregnancy. You may also be referred to other specialists such as:

. Pediatric surgeons

. Pediatric urologists

. Pediatric orthopedic surgeons

. Plastic surgeons

. Pediatric cardiologists

. Pediatric cardiovascular surgeons

. Neonatologists

Your doctors and others on your health care team learn as much as possible about your twins’ anatomy, functional capabilities and prognosis to form a treatment plan for your twins.

Delivery

A C-section is planned ahead of time, often two to four weeks before your due date.

After your conjoined twins are born, they’re fully evaluated. With this information, you and your health care team members can make decisions regarding their care and whether separation surgery is appropriate.

Separation surgery

Separation surgery is an elective procedure done usually a year or more after birth to allow time for planning and preparation. Sometimes an emergency separation may be needed if one of the twins dies, develops a life-threatening condition or threatens the survival of the other twin.

Many complex factors must be considered as part of the decision to pursue separation surgery. Each set of conjoined twins presents a unique set of considerations due to variations in anatomy. Issues include:

. Whether the twins share vital organs, such as the heart

. Whether the twins are healthy enough to withstand separation surgery

. Odds of successful separation

. Type and extent of reconstructive surgery needed for each twin after separation

. Type and extent of functional support needed after separation

. What challenges the twins face if left conjoined

Recent advances in prenatal imaging, critical care and anesthetic care have improved outcomes in separation surgery. After separation surgery, pediatric rehabilitation services are crucial to assist with appropriate skill development through physical, occupational and speech therapies.

If surgery isn’t an option

If separation surgery isn’t possible or if you decide not to pursue the surgery, your team can help you meet the medical care needs of your twins.

If the circumstances are grave, medical comfort care — such as nutrition, fluids, human touch and pain relief — is provided.

Source:

. https://www.mayoclinic.org/diseases-conditions/conjoined-twins/symptoms-causes/syc-20353910

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